Regional honors in Houston, Arizona and Pittsburgh, national healthcare industry recognition and eight Culture Excellence awards bring Castle's 2026 Top Workplaces honors to 13

FRIENDSWOOD, Texas, Nov. 12, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that it has earned regional Top Workplaces awards in Houston, Arizona and Pittsburgh, along with national recognition through the Top Workplaces Healthcare Industry award and eight Top Workplaces Culture Excellence awards. Based on employee feedback, these honors reflect Castle's continued commitment to creating a workplace where people feel valued, supported and connected to a shared purpose.

"Our strong culture is built through the everyday actions of our people, who care deeply about their work and one another," said Derek Maetzold, president and chief executive officer of Castle Biosciences. "Our Castle team members bring that commitment to life through their dedication to the patients and clinicians we serve and the support they show their colleagues. We are humbled by the culture that we continue to build together and remain focused on helping our people grow, contribute and thrive."

Castle's latest regional and industry honors include:

• Houston Top Workplaces: Recognized for the sixth consecutive year by the Houston Chronicle, ranking 11th among companies with 500+ employees.
• Arizona Top Workplaces: Recognized for the fifth consecutive year by AZ Central, ranking 11th among companies with 500+ employees.
• Pittsburgh Top Workplaces: Recognized for the second consecutive year by The Pittsburgh Post-Gazette, ranking 3rd among companies with 400+ employees.
• Top Workplaces Healthcare Industry: Recognized for the fourth consecutive year as a national leader in the healthcare industry.

Castle also received eight national Top Workplaces Culture Excellence awards, recognizing distinct aspects of the Company's employee experience:

• Compensation & Benefits (2022-2026), for providing packages their employees believe are fair for their work compared to others in the industry.
• Employee Appreciation (2022-2026), for believing in the self-sustaining performance and positivity boosts that result from genuine employee appreciation.
• Employee Well-Being (2021-2026), for putting health and wellness at the center of workplace culture.
• Innovation (2022-2026), for creating a culture where new ideas are encouraged, enabling employees to reach their full potential.
• Leadership (2022-2026), for organizational leaders who inspire confidence in their employees and in the direction of the Company and use employee feedback to inform decisions.
• Professional Development (2022-2026), for developing their employees' careers and enabling their people to grow professionally.
• Purpose & Values (2022-2026), for successfully communicating the company mission and integrating those aspirations into the culture.
• Work-Life Flexibility (2023-2026), for building a culture that empowers employees to meet the demands of their personal lives while maintaining high performance.

Together, these distinctions highlight the breadth of Castle's commitment to its employees, from supporting professional growth and well-being to encouraging new ideas and connecting individual contributions to the Company's mission.

The awards follow Castle's previously announced 2026 USA TODAY Top Workplaces USA award, its fifth consecutive year receiving that national honor. With these additional recognitions, Castle has earned 13 Top Workplaces awards in 2026.

Top Workplaces awards are determined by employee responses to a confidential survey conducted by Energage, the organization behind the recognition program. The survey evaluates the employee experience across key aspects of workplace culture. Regional and industry awards recognize outstanding employers within their respective markets, while Culture Excellence awards spotlight specific workplace strengths.

For more information about the Top Workplaces program, visit topworkplaces.com.

About Castle Biosciences
Castle Biosciences (Nasdaq: CSTL) is a leading diagnostics company improving health through innovative tests that guide patient care. With a primary focus in dermatologic and gastroenterological disease, we develop personalized, clinically actionable solutions that help improve disease management and patient outcomes.

We put people first—empowering patients and clinicians and informing care decisions through rigorous science and advanced molecular tests that support more confident treatment planning. To learn more, visit www.CastleBiosciences.com and connect with us on LinkedIn, Instagram, Facebook and X. 

DecisionDx-Melanoma, DecisionDx-CMSeq, i31-SLNB, i31-ROR, DecisionDx-SCC, MyPath Melanoma, AdvanceAD-Tx, TissueCypher, Esopredict, DecisionDx-UM, DecisionDx-PRAME and DecisionDx-UMSeq are trademarks of Castle Biosciences, Inc.

Investor Contact:
Camilla Zuckero
czuckero@castlebiosciences.com 

Media Contact:
Allison Marshall
amarshall@castlebiosciences.com 

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SOURCE Castle Biosciences, Inc.